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EZSolution CHIR99021

SKU
E-2311
  • CAS:252917-06-9
  • Formula:C22H18Cl2N8
  • MW:465.34
  • Appearance:Liquid
  • Purity:98% by HPLC
Product Name Qty
EZSolution CHIR99021
5 mg
$206.07
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CHIR99021 is an aminopyrimidine derivative that inhibits GSK3α and GSK3β. It activates glycogen synthesis in CHO-IR cells and in isolated type 1 diabetic rat skeletal muscle and it has also been shown to induce the reprogramming of murine and human somatic cells into stem cells

More Information
Alternate Name/Synonyms
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021
SKU
E-2311
CAS #
252917-06-9
Chemical Name
6-((2-((4-(2,4-Dichlorophenyl)-5-(4-methyl-1H-imidazol-2-yl)pyrimidin-2-yl)amino)ethyl)amino)nicotinonitrile; CT99021
Chemical Formula
C22H18Cl2N8
Molecular Weight
465.34
Appearance
Liquid
Purity
98% by HPLC
Melting Point
316.33 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Endocrinological Disorders
USE
CHIR99021 is GSK3β kinase inhibitor enhances glucose metabolism in type 2 diabetes
MDL NUMBER
MFCD11846251
CHEMACX
X1755647-3
INCHI
InChI=1S/C22H18Cl2N8/c1-13-10-29-21(31-13)17-12-30-22(32-20(17)16-4-3-15(23)8-18(16)24)27-7-6-26-19-5-2-14(9-25)11-28-19/h2-5,8,10-12H,6-7H2,1H3,(H,26,28)(H,29,31)(H,27,30,32)
SMILES
CC1=CNC(=N1)C2=CN=C(N=C2C3=C(C=C(C=C3)Cl)Cl)NCCNC4=NC=C(C=C4)C#N
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
GHS PICTOGRAMS
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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