EZSolution SB-431542

SKU
E-2320
  • CAS:301836-41-9
  • Formula:C22H18N4O3
  • MW:384.39
  • Appearance:Liquid
  • Purity:98%
Product Name Qty
EZSolution SB-431542
1 mg
$89.34

SB-431542 is a potent and selective inhibitor of TGF-β superfamily type I activin receptor-like kinase (ALK) receptors, specifically ALK4, ALK5 and ALK7. Inhibition of TGF-β signaling is known to induce the de-repression of epithelial fate and thus was hypothesized to benefit the reprogramming process. 

More Information
Alternate Name/Synonyms
4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
SKU
E-2320
CAS #
301836-41-9
Chemical Name
4-[4-(1,3-benzodioxol-5-yl)-5-pyridin-2-yl-1H-imidazol-2-yl]benzamide
Chemical Formula
C22H18N4O3
Molecular Weight
384.39
Appearance
Liquid
Purity
98%
Stability
N/A
Melting Point
315.72 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A specific and selective inhibitor of TGF-ß type I ALK receptors and Smad3.It also suppressed the TGF-beta-induced proliferation of osteosarcoma
MDL NUMBER
MFCD05865244
CHEMACX
X1430393-8
INCHI
InChI=1S/C22H16N4O3/c23-21(27)13-4-6-14(7-5-13)22-25-19(20(26-22)16-3-1-2-10-24-16)15-8-9-17-18(11-15)29-12-28-17/h1-11H,12H2,(H2,23,27)(H,25,26)
SMILES
c1ccnc(c1)c2c(nc([nH]2)c3ccc(cc3)C(=O)N)c4ccc5c(c4)OCO5
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Promo text for AGS discount
N/A
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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