- MW:306.8 Da
- Appearance:Dark red-brown powder
Originally isolated from a marine sponge, Fascaplysin is selective CYCLIN-DEPENDENT KINASE 4 INHIBITOR (in a ATP competitive manner). Selective CDK4/cyclin D1 (IC50 = 350 nM) inhibitor (in an ATP competitive manner).
Fascaplysin is an inhibitor of Cdk6. Fascaplysin exert anti-tumor effects through apoptotic and anti-angiogenesis pathways. Fascaplysin has recently been shown to be a DNA intercalator.
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Avoid contact with skin, eyes or clothing. Use personal protective equipment as required.Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation. Corrosive hazard. Wear protective gloves/clothing and eye/face protection. Thermal decomposition can lead to release of toxic/corrosive gases and vapors.|