Fasudil, Monohydrochloride

SKU

F-2327

CAS:105628-07-7
Formula:C₁₄H₁₇N₃O₂S•HCl
MW:327.83
Appearance:White to off-white solid
Purity:≥99% by HPLC

SDS

CofA

Starting at $98.28

Product Name	Qty
Fasudil, Monohydrochloride 10 mg $98.28
Fasudil, Monohydrochloride 50 mg $368.52

Details

A cell-permeable Ca²⁺ antagonist and vasodilator. Inhibits protein kinase A (Ki = 1.6 µM), protein kinase G (Ki = 1.6 µM), myosin light chain kinase (Ki = 36 µM) and Rho kinase (ROCK; IC₅₀ = 10.7 µM. Fasudil also mobilizes adult neural stem cells in vivo.

Specifications

More Information

SKU

F-2327

CAS #

105628-07-7

Chemical Name

1-(5-Isoquinolinesulfonyl)homopiperazine, Monohydrochloride Salt; HA-1077, Monohydrochloride; AT-877

Chemical Formula

C₁₄H₁₇N₃O₂S•HCl

Molecular Weight

327.83

Appearance

White to off-white solid

Purity

≥99% by HPLC

Solubility

Soluble in Water (175 mg/ml) or DMSO (10 mg/ml)

Stability

N/A

Storage Temp

-20°C

PubChecm ID

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GHS PICTOGRAMS

Citations

Citations	Regulation of the mesangial cell myofibroblast phenotype by actin polymerization