Feglymycin

SKU
F-2423
  • CAS:209335-49-9
  • Formula:C95H97N13O30
  • MW:1900.9
  • Appearance:Tan solid
  • Purity:>95% by HPLC
Product Name Qty
Feglymycin
1 mg
$349.58
Feglymycin
5 mg
$1,223.53

Description

Feglymycin is an amphoteric, 13-member, linear peptide featuring 3,5-dihydroxyphenylalanine and a terminal dicarboxylate amino acid, isolated from Streptomyces in 1999.

Feglymycin is a potent antiviral agent with antibacterial activity, including against MRSA. Feglymycin specifically inhibits the enzymes MurA and MurC and inhibits cell-to-cell transfer between HIV-infected T cells, uninfected CD4+ T cells, and the DC-SIGN-mediated viral transfer to CD4+ T cells.

 

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
SKU
F-2423
CAS #
209335-49-9
Chemical Formula
C95H97N13O30
Molecular Weight
1900.9
Appearance
Tan solid
Purity
>95% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
A potent antiviral agent.Feglymycin, a novel inhibitor of the replication of the human immunodeficiency virus
INCHI
InChI=1S/C95H97N13O30/c1-43(2)73(99-90(132)78(50-27-59(113)37-60(114)28-50)101-84(126)72(96)46-10-18-55(109)19-11-46)85(127)106-81(53-33-65(119)40-66(120)34-53)93(135)103-77(49-16-24-58(112)25-17-49)89(131)108-82(54-35-67(121)41-68(122)36-54)94(136)104-76(48-14-22-57(111)23-15-48)88(130)107-79(51-29-61(115)38-62(116)30-51)91(133)100-74(44(3)4)86(128)105-80(52-31-63(117)39-64(118)32-52)92(134)102-75(47-12-20-56(110)21-13-47)87(129)97-69(26-45-8-6-5-7-9-45)83(125)98-70(95(137)138)42-71(123)124/h5-25,27-41,43-44,69-70,72-82,109-122H,26,42,96H2,1-4H3,(H,97,129)(H,98,125)(H,99,132)(H,100,133)(H,101,126)(H,102,134)(H,103,135)(H,104,136)(H,105,128)(H,106,127)(H,107,130)(H,108,131)(H,123,124)(H,137,138)/t69-,70-,72?,73-,74-,75?,76?,77?,78?,79?,80?,81?,82?/m0/s1
SMILES
CC(C)[C@@H](C(=O)NC(C1=CC(=CC(=C1)O)O)C(=O)NC(C2=CC=C(C=C2)O)C(=O)NC(C3=CC(= CC(=C3)O)O)C(=O)NC(C4=CC=C(C=C4)O)C(=O)NC(C5=CC(=CC(=C5)O)O)C(=O)N[C@@H](C(C )C)C(=O)NC(C6=CC(=CC(=C6)O)O)C(=O)NC(C7=CC=C(C=C7)O)C(=O)N[C@@H](CC8=CC=CC=C 8)C(=O)N[C@@H](CC(=O)O)C(=O)O)NC(=O)C(C9=CC(=CC(=C9)O)O)NC(=O)C(C1=CC=C(C=C1 )O)N
Certificate of Analysis 1
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