Florfenicol

SKU
F-2433
  • CAS:73231-34-2
  • Formula:C12H14Cl2FNO4S
  • MW:358.2
  • Appearance:White solid
  • Purity:>99% by HPLC
Product Name Qty
Florfenicol
25 mg
$75.75
Florfenicol
100 mg
$264.51
*Please inquire the availability for this product. Florfenicol is synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine, first synthesised at Schering in 1980. By replacing the hydroxy group, it was rationalised that chloramphenicol resistance via chloramphenicol acetyltransferase could be eliminated. Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Florfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Florfenicol has been extensively studied with over 400 literature citations.
More Information
Alternate Name/Synonyms
(-)Florfenicol, Sch 25298
SKU
F-2433
CAS #
73231-34-2
Chemical Formula
C12H14Cl2FNO4S
Molecular Weight
358.2
Appearance
White solid
Purity
>99% by HPLC
Solubility
Soluble in ethanol (50 mg/ml), DMSO (100 mM), water (132 mg/ml, pH 7), acetone, and DMF
Melting Point
153-157 °C
Storage Temp
4°C
THERAPEUTIC AREA
Infectious Diseases
USE
Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria
MDL NUMBER
MFCD00864834
INCHI
InChI=1S/C12H14Cl2FNO4S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-15)16-12(18)11(13)14/h2-5,9-11,17H,6H2,1H3,(H,16,18)/t9-,10-/m1/s1
SMILES
CS(=O)(=O)c1ccc(cc1)[C@H]([C@@H](CF)NC(=O)C(Cl)Cl)O
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