- Appearance:White solid
- Purity:>99% by HPLC
*Please inquire the availability for this product. Florfenicol is synthesised from thiamphenicol by replacing the 3-hydroxy group with fluorine, first synthesised at Schering in 1980. By replacing the hydroxy group, it was rationalised that chloramphenicol resistance via chloramphenicol acetyltransferase could be eliminated. Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria. Florfenicol acts by binding to the 23S sub-unit of the 50S ribosome, inhibiting protein synthesis. Florfenicol has been extensively studied with over 400 literature citations.
(-)Florfenicol, Sch 25298
>99% by HPLC
Soluble in ethanol (50 mg/ml), DMSO (100 mM), water (132 mg/ml, pH 7), acetone, and DMF
Florfenicol is a broad spectrum antibiotic with good activity against Gram negative and anaerobic bacteria