- MW:246.20 Da
- Appearance:White or almost white crystalline powder
- Purity: ≥ 98.5 % HPLC
Floxuridine is a pyramidine analogue that acts as an antineoplastic antimetabolite. Floxuridine inhibits cell division by inhibiting thymidylate formation, which in turn prevents the formation of dTTP. Via this mechanism, floxuridine exerts an anti-cancer effect.
In clinical oncology, floxuridine is a preferred drug for the treatment of cancers of the colon which have metastasized to the liver. For this purpose, it is typically administered via the hepatic artery. Administration often occurs in conjunction with folinic acid, which enhances the drug's effects. In research, it is primarily used in studies of liver cancers and their treatments, as well as in ongoing studies on the mechanisms of chemotherapeutic drugs.
|Handling||Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.|