Fludarabine Phosphate

SKU
F-2329
  • CAS:75607-67-9
  • Formula:C10H13FN5O7P
  • MW:365.21
  • Appearance:White Solid
  • Purity:98%
Product Name Qty
Fludarabine Phosphate
10 mg
$85.43
Fludarabine Phosphate
50 mg
$336.03
A chemotherapy drug used in the treatment of hematological malignancies. Fludarabine phosphate is rapidly dephosphorylated to 2-fluoro-ara-A and then phosphorylated intracellularly by deoxycytidine kinase to the active triphosphate, 2-fluoro-ara-ATP. This metabolite may inhibit DNA polymerase-, ribonucleotide reductase and DNA primase, thereby interrupting DNA synthesis and inhibiting tumor cell growth.
More Information
Alternate Name/Synonyms
[(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)- 3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid; Fludara
SKU
F-2329
CAS #
75607-67-9
Chemical Name
[(2R,3R,4S,5R)-5-(6-amino-2-fluoro-purin-9-yl)- 3,4-dihydroxy-oxolan-2-yl]methoxyphosphonic acid; Fludara
Chemical Formula
C10H13FN5O7P
Molecular Weight
365.21
Appearance
White Solid
Purity
98%
Solubility
Soluble in DMSO or H2O (5 mg/ml)
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Fludarabine phosphate (Fludara) is a chemotherapy drug used in the treatment of hematological malignancies
MDL NUMBER
MFCD00866418
CHEMACX
X1014395-4
INCHI
InChI=1S/C10H13FN5O7P/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(18)5(17)3(23-9)1-22-24(19,20)21/h2-3,5-6,9,17-18H,1H2,(H2,12,14,15)(H2,19,20,21)/t3-,5-,6+,9-/m1/s1
SMILES
c1nc2c(nc(nc2n1[C@H]3[C@H]([C@@H]([C@H](O3)COP(=O)(O)O)O)O)F)N
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and moisture
HandlingProtect from air and moisture
UN #'SNot Applicable
Packing GroupNot Applicable
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