FTI-277 Trifluoroacetate salt
- Appearance:Off-white, waxy Solid
- Purity:95% by HPLC
Pro-drug form of FTI-276 that acts as a highly potent and selective inhibitor of FTase (IC = 50 nM). Inhibits H-Ras processing in whole cells (IC = 100 nM), but does not inhibit geranylgeranylated Rap1A processing.
Off-white, waxy Solid
95% by HPLC
DMSO (100 mg/ml)
The farnesyl transferase inhibitor, FTI-277, inhibits growth and induces apoptosis in drug-resistant myeloma tumor cells.
Hygroscopic. Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 week at -70°C.
|Handling||Hygroscopic. Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 week at -70°C.|