- MW:458.6 Da
- Appearance:Beige crystalline powder
MetAP-2 inhibitor.Fumagillin is an inhibitor of endothelial cell proliferation and angiogenesis. Fumagillin is also being investigated as potential treatment of intestinal microsporidiosis.We investigated the role of fumagillin as a potential therapy in experimental Pulmonary Hypertension (PH). 1.Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents pulmonary hypertension in monocrotaline-injured rats.
|Handling||Avoid contact with skin, eyes, and personal clothing. Wash hands thoroughly after handling. Avoid breathing fumes. Use only with adequate ventilation. Wear suitable protective clothing, gloves, and eye/face protection. Keep away from sources of ignition. Minimize dust generation and accumulation. Keep container tightly closed. Open and handle container with care. Do not eat, drink, or smoke while handling.|