- MW: 1001.9 Da
- Appearance:Off-white to light yellow solid
- Purity:≥95% (HPLC)
Cell permeable Fluorescent Ca2+ indicator. Hydrolysis by non-specific esterases traps the indicator in the cytosol.
Fura-2 pentakis(acetoxymethyl) ester
Off-white to light yellow solid
Soluble in DMSO
FURA 2/AM is the cell-permeable ester form of FURA 2 (sc-221644 & sc-202163), which is a fluorescent chelator (Kd = 224 nM) selective for Ca2+ over other ions and offers 30 times greater fluorescence intensity than QUIN 2 (sc-202303). FURA 2/AM is rapidly metabolized in the cell by cytoplasmic esterases; yielding the active dye FURA 2. FURA 2/AM can be used as a probe to determine calcium concentrations in many cellular systems, including: cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max = 362 nm, emission max = 512 nm) differ from those during high calcium conditions (excitation max = 335 nm, emission max = 505 nm).
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Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
|Handling||Provide appropriate exhaust ventilation at places where dust is formed. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.|