Fura-2(AM)

SKU
F-1040
  • CAS:108964-32-5
  • Formula:C44H47N3O24
  • MW: 1001.9 Da
  • Appearance:Off-white to light yellow solid
  • Purity:≥95% (HPLC)

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Product Name Qty
Fura-2(AM)
1 mg
$165.57
Fura-2(AM)
20x50 ug
$215.23

Cell permeable Fluorescent Ca2+ indicator. Hydrolysis by non-specific esterases traps the indicator in the cytosol.

More Information
Alternate Name/Synonyms
Fura-2 pentakis(acetoxymethyl) ester
SKU
F-1040
CAS #
108964-32-5
Chemical Name
acetyloxymethyl 2-[6-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]-1-benzofuran-2-yl]-1,3-oxazole-5-carboxylate
Chemical Formula
C44H47N3O24
Molecular Weight
1001.9 Da
Appearance
Off-white to light yellow solid
Purity
≥95% (HPLC)
Solubility
Soluble in DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Not Applicable
USE
FURA 2/AM is the cell-permeable ester form of FURA 2 (sc-221644 & sc-202163), which is a fluorescent chelator (Kd = 224 nM) selective for Ca2+ over other ions and offers 30 times greater fluorescence intensity than QUIN 2 (sc-202303). FURA 2/AM is rapidly metabolized in the cell by cytoplasmic esterases; yielding the active dye FURA 2. FURA 2/AM can be used as a probe to determine calcium concentrations in many cellular systems, including: cardiac myocytes, vascular smooth muscle cells, and medullary collecting tubules. Spectral properties in the presence of low calcium concentrations (excitation max = 362 nm, emission max = 512 nm) differ from those during high calcium conditions (excitation max = 335 nm, emission max = 505 nm).
Handling
Provide appropriate exhaust ventilation at places where dust is formed. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
Handling Provide appropriate exhaust ventilation at places where dust is formed. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
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