Galiellalactone

SKU
G-2503
  • CAS:133613-71-5
  • Formula:C11H14O3
  • MW:194.2
  • Appearance:White Lyophilisate
  • Purity:>95% by HPLC
Product Name Qty
Galiellalactone
1 mg
$363.56
Galiellalactone
5 mg
$1,272.47
*Please inquire the availability for this product. Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500 nM, blocking the binding of the activated Stat3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor.
More Information
SKU
G-2503
CAS #
133613-71-5
Chemical Formula
C11H14O3
Molecular Weight
194.2
Appearance
White Lyophilisate
Purity
>95% by HPLC
Solubility
Soluble in 100% ethanol, methanol, DMF, and DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Galiellalactone is a Direct Inhibitor of STAT3 in Prostate Cancer Cell
MDL NUMBER
MFCD11111607
INCHI
InChI=1S/C11H14O3/c1-6-4-7-2-3-9-11(7,13)8(5-6)10(12)14-9/h5-7,9,13H,2-4H2,1H3/t6-,7+,9+,11-/m0/s1
SMILES
O=C/1O[C@@H]3CC[C@@H]2C[C@@H](/C=C\1[C@@]23O)C
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