- Appearance:White Lyophilisate
- Purity:>95% by HPLC
*Please inquire the availability for this product. Galiellalactone was originally isolated from Galiella rufa as a plant growth regulator. Recently it was shown to inhibit IL-6 induced SEAP expression with IC50 values of 250-500 nM, blocking the binding of the activated Stat3 dimers to their DNA binding sites without inhibiting the tyrosine and serine phosphorylation of the Stat3 transcription factor.
>95% by HPLC
Soluble in 100% ethanol, methanol, DMF, and DMSO
Galiellalactone is a Direct Inhibitor of STAT3 in Prostate Cancer Cell