Gemcitabine Hydrochloride

SKU
G-2336
  • CAS:122111-03-9
  • Formula:C9H11F2N3O4•HCl
  • MW:299.66
  • Appearance:White solid
  • Purity:≥98% by HPLC

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Product Name Qty
Gemcitabine Hydrochloride
25 mg
$96.82
Gemcitabine Hydrochloride
100 mg
$313.24

A nucleoside analog of deoxycytidine used in chemotherapy to treat various types of cancer. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis.

More Information
Alternate Name/Synonyms
Gamcitabine; Gemcitera; Gemsar; Gemzar; LY-188011
SKU
G-2336
CAS #
122111-03-9
Chemical Name
2′,2′-difluoro-2′-deoxycytidine
Chemical Formula
C9H11F2N3O4•HCl
Molecular Weight
299.66
Appearance
White solid
Purity
≥98% by HPLC
Solubility
Soluble in DMSO (10 mg/ml) or H2O (25 mg/ml)
Storage Temp
-20°C
Certificate of Analysis 1
GHS PICTOGRAMS
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