Gentamycin Sulfate, USP Grade

SKU
G-1067
  • CAS:1405-41-0
  • Formula:C21H43N5O7 • H2SO4
  • MW:575.6 Da
  • Appearance:White to off-white powder

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Starting at $43.83

Product Name Qty
Gentamycin Sulfate, USP Grade
1 g
$43.83
Gentamycin Sulfate, USP Grade
5 g
$155.61

Description

Gentamicin Sulfate is an aminoglycoside complex and a broad-spectrum antibiotic created by fermentation of Micromonospora purpurea. It can effectively inhibit disease manifestations produced by Staphylococcus aureus, Klebsiella pneumoniae and other pathogenic organisms. This compound can also inhibit protein synthesis by binding to L6 protein of 50S ribosomal subunit.

Applications

• Used in treating primary and secondary bacterial infections
• Used in treating mastitis in cattle
• Used in cell and tissue culture and also for transport of cell cultures, certain clinical specimens containing viruses or specimens in which overgrowth of bacteria should be avoided

More Information
Alternate Name/Synonyms
Gentamicin; Gentimicin Sulfate; Garamycin; Gentiomycin C
SKU
G-1067
CAS #
1405-41-0
Chemical Name
2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
Chemical Formula
C21H43N5O7 • H2SO4
Molecular Weight
575.6 Da
Appearance
White to off-white powder
Purity
N/A
Solubility
Soluble in DMSO
Melting Point
102-108°C
Preparation
N/A
Storage Temp
Store desiccated at +4°C
THERAPEUTIC AREA
Infectious diseases
USE
Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Reported to have low toxicity to mammalian cells and viruses at certain concentrations, useful for long-term tissue culture studies with viruses. This compound is a mixture of Gentamycin c1, c1a and c2.
Merck Index
13.4403.2001
RTECS
N/A
Handling
Warning! Toxic. May be Carcinogenic. May be Teratogenic. Ensure good ventilation/exhaustion at the workplace. Avoid direct contact with skin and eyes.
Citations
MEMBRANE TRANSPORTERS, ION CHANNELS AND PUMPS: Ischemia-induced stimulation of cerebral microvascular endothelial cell Na-K-Cl cotransport involves p38 and JNK MAP kinases Breanna K. Wallace, Karen A. Jelks, and Martha E. O'Donnell Am J Physiol Cell Physiol, Feb 2012; 302: C505 - C517.
Citations_Hyperlink
http://ajpcell.physiology.org/cgi/reprint/302/3/C505
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
GHS PICTOGRAMS
Handling Warning! Toxic. May be Carcinogenic. May be Teratogenic. Ensure good ventilation/exhaustion at the workplace. Avoid direct contact with skin and eyes.
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