Gilvocarcin V

SKU
G-2519
  • CAS:77879-90-4
  • Formula:C27H26O9
  • MW:494.5
  • Appearance:Yellow crystals
  • Purity:>95% by HPLC
Product Name Qty
Gilvocarcin V
0.5 mg
$310.51
Gilvocarcin V
25 mg
$1,010.57
*Please inquire the availability for this product. Gilvocarcin V is the major analogue of a complex of C-glycoside antitumor actives isolated from a Streptomyces sp.. Gilvocarcin V contains a vinyl group in the 8-position, and is the most potent analogue of the complex. It is thought to act as an inhibitor of the catalytic activity of human topoisomerase II. The metabolite displays potent antibacterial, antifungal, antiviral and antitumor activity. Recent research suggests that the gilvocarcins act as photoactivated cross-linkers of DNA to histones.
More Information
Alternate Name/Synonyms
Anandimycin A, Toromycin, 1072B
SKU
G-2519
CAS #
77879-90-4
Chemical Formula
C27H26O9
Molecular Weight
494.5
Appearance
Yellow crystals
Purity
>95% by HPLC
Solubility
Soluble in DMSO, DMF (moderately), methanol (moderately), ethanol (moderately), and water (poor)
Melting Point
322.54 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A metabolite that displays potent antibacterial, antifungal and antiviral activity
MDL NUMBER
MFCD01939442
INCHI
InChI=1S/C27H26O9/c1-5-12-8-15-19(17(9-12)33-3)14-10-18(34-4)21-16(29)7-6-13(20(21)25(14)36-27(15)32)26-23(31)22(30)24(35-26)11(2)28/h5-11,22-24,26,28-31H,1H2,2-4H3/t11?,22?,23?,24?,26-/m1/s1
SMILES
CC(C1C(C([C@H](O1)c2ccc(c3c2c4c(cc3OC)c5c(cc(cc5OC)C=C)c(=O)o4)O)O)O)O
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