Gö 6976
SKU
G-1017
- CAS:136194-77-9
- Formula:C24H18N4O
- MW:378.4
- Appearance:Off-White to Yellow Solid
- Purity:≥99%
SDS
CofA
Cell-permeable. A potent protein kinase C (PKC) inhibitor (IC₅₀ = 7.9 nM). In vitro, discriminates between Ca²⁺- dependent and -independent isoforms of PKC; selectively inhibits PKCα and PKCβ1 (IC₅₀ values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKCδ, -ε, or -ζ (IC₅₀>3μM).
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http://mcb.asm.org/content/24/19/8374.full.pdf+html
More Information
Alternate Name/Synonyms
Go6976; PD 406976
SKU
G-1017
CAS #
136194-77-9
Chemical Name
5,6,7,13-Tetrahydro-13-methyl-5-oxo-12Hindolo[ 2,3-a]py-rrolo[3,4-c]carbazole-12- propanenitrile
Chemical Formula
C24H18N4O
Molecular Weight
378.4
Appearance
Off-White to Yellow Solid
Purity
≥99%
Solubility
H2O (10 mg/ml)
Storage Temp
-20°C
Certificate of Analysis 1
Certificate of Analysis 2