Gossypol

SKU
G-1221
  • CAS:303-45-7
  • Formula:C30H30O8
  • MW:518.6 Da
  • Appearance:Off-white to yellow Solid
  • Purity:90%

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Product Name Qty
Gossypol
100 mg
$102.52

Description

Shows anti-tumor, anti-viral and anti-oxidant actions. Small molecule inhibitor of Bcl-2/Bcl-XL. Induces apoptosis. Synergizes with radiation and chemotherapyin vitro. Gossypol is used as a contraceptive for men.

More Information
Alternate Name/Synonyms
Pogosin; 2,2′-bis(8-Formyl-1,6,7-trihydroxy-5-isopropyl-3-methylnaphthalene)
SKU
G-1221
CAS #
303-45-7
Chemical Name
7-(8-formyl-1,6,7-trihydroxy-3-methyl-5-propan-2-ylnaphthalen-2-yl)-2,3,8-trihydroxy-6-methyl-4-propan-2-ylnaphthalene-1-carbaldehyde
Chemical Formula
C30H30O8
Molecular Weight
518.6 Da
Appearance
Off-white to yellow Solid
Purity
90%
Solubility
Soluble in 100% Ethanol (25mg/ml); DMF, Acetone, or DMSO. Insoluble in Water.
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Gossypol Induces Apoptosis by Activating p53 in Prostate Cancer Cells
Merck Index
Merck Index: 14: 4528
MDL NUMBER
MFCD00017352
CHEMACX
X1009723-5
INCHI
InChI=1S/C30H30O8/c1-11(2)19-15-7-13(5)21(27(35)23(15)17(9-31)25(33)29(19)37)22-14(6)8-16-20(12(3)4)30(38)26(34)18(10-32)24(16)28(22)36/h7-12,33-38H,1-6H3
SMILES
Cc1cc2c(c(c(c(c2C(C)C)O)O)C=O)c(c1c3c(cc4c(c3O)c(c(c(c4C(C)C)O)O)C=O)C)O
Peptide sequence
Not Applicable
RTECS
DU3100000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation
Hazard Image
Yes
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing. Use personal protective equipment as required. Wash contaminated clothing before reuse. Do not breathe dust/fume/gas/mist/vapors/spray. Do not eat, drink or smoke when using this product. Use with local exhaust ventilation
UN #'S Not Applicable
Packing Group Not Applicable
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