Griseofulvin

SKU
G-1243
  • CAS:126-07-8
  • Formula:C17H17CIO6
  • MW:352.1
  • Appearance:White solid.
  • Purity:>99% by HPLC

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Product Name Qty
Griseofulvin
25 mg
$150.77
Griseofulvin
100 mg
$508.12

Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect to the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.

More Information
Alternate Name/Synonyms
Amudane, Grisovin, Fulvicin, Curling factor, Gricin, Grifulvin, Grisactin, Fulcin, Norofulvin, Likuden, Idifulvin NSC 34533
SKU
G-1243
CAS #
126-07-8
Chemical Formula
C17H17CIO6
Molecular Weight
352.1
Appearance
White solid.
Purity
>99% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Stability
N/A
Melting Point
218-220 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Griseofulvin is an antifungal drug. It is used both in animals and humans, to treat fungal infections of the skin
MDL NUMBER
MFCD00082343
INCHI
InChI=1S/C17H17ClO6/c1-8-5-9(19)6-12(23-4)17(8)16(20)13-10(21-2)7-11(22-3)14(18)15(13)24-17/h6-8H,5H2,1-4H3/t8-,17+/m1/s1
SMILES
C[C@@H]1CC(=O)C=C([C@]12C(=O)c3c(cc(c(c3O2)Cl)OC)OC)OC
Certificate of Analysis 1
Promo text for AGS discount
N/A
GHS PICTOGRAMS
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