SDS
CofA
Description
Carrier of nitric oxide, relaxing smooth muscles and inhibiting platelet activation.
Not for human therapeutic use or for medicinal purposes. For research applications only.
More Information
Alternate Name/Synonyms
S-nitrosoglutathione; SNOG; Nitrosoglutathione; Glutathione thionitrite; N-(N-L-gamma-Glutamyl-S-nitroso-L-cysteinyl)glycine
SKU
G-2343
CAS #
57564-91-7
Chemical Name
(2S)-2-amino-5-[[(2R)-1-(carboxymethylamino)-3-nitrososulfanyl-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
Chemical Formula
C10H16N4O7S
Molecular Weight
336.3
Appearance
Pink solid
Purity
≥98% by HPLC
Solubility
DMSO (10 mg/mL) or PBS (35 mg/mL)
Melting Point
170 °C
Storage Temp
-20ºC
THERAPEUTIC AREA
Genetic Disorders
USE
GSNO is spontaneously releasing nitric oxide donor which inhibits NFκB in pulmonary diseases such as cystic fibrosis
MDL NUMBER
MFCD00214341
CHEMACX
X1093719-4
INCHI
InChI=1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
SMILES
C(CC(=O)N[C@@H](CSN=O)C(=O)NCC(=O)O)[C@@H](C(=O)O)N
RTECS
MC0558000
Handling
Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required. Use with local exhaust ventilation. Do not breathe dust/fume/gas/mist/vapors/spray. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection.
Certificate of Analysis 1
| GHS PICTOGRAMS |  |
|---|---|
| Handling | Ensure adequate ventilation, especially in confined areas. Use personal protective equipment as required. Use with local exhaust ventilation. Do not breathe dust/fume/gas/mist/vapors/spray. Handle in accordance with good industrial hygiene and safety practice. Corrosive hazard. Wear protective gloves/clothing and eye/face protection. |
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