GW-5074

SKU
G-2501
  • CAS:220904-83-6
  • Formula:C5H8Br2INO2
  • MW:520.94
Product Name Qty
GW-5074
5 mg
$131.00

Cell-permeable. A potent inhibitor of cRAF1 kinase (IC₅₀ = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects in vivo via a mechanism that is independent of MEK, ERK, and Akt signaling.

More Information
Alternate Name/Synonyms
3-(3,5-Dibromo-4-hydroxybenzyliden)-5-iodo-1,3-dihydroindol-2-one
SKU
G-2501
CAS #
220904-83-6
Chemical Formula
C5H8Br2INO2
Molecular Weight
520.94
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