GYY 4137

SKU
G-2349
  • CAS:106740-09-4
  • Formula:C11H15NO2PS2
  • MW:376.47
  • Appearance:White solid
  • Purity:≥95% by HPLC
Product Name Qty
GYY 4137
5 mg
$68.34
GYY 4137
25 mg
$273.38

A slow-releasing, water-soluble hydrogen sulfide (H2S) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models.

Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.

More Information
SKU
G-2349
CAS #
106740-09-4
Chemical Name
p-Methoxyphenyl)morpholino-phosphinodithioic acid
Chemical Formula
C11H15NO2PS2
Molecular Weight
376.47
Appearance
White solid
Purity
≥95% by HPLC
Solubility
DMSO (15 mg/ml) or water (30 mg/ml)
Storage Temp
-20°C
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