SDS
CofA
Potent anti-inflammatory and anti-neoplastic agent. Induces a CD95 death receptor-independent apoptosis even when the mitochondria protecting proteins Bcl-xL or Bcl-2 are overexpressed. Also an inhibitor of NF-B.
More Information
SKU
H-1300
CAS #
6754-13-8
Chemical Name
(3AR,5R,5AR,8AR,9S,9AS)-9-HYDROXY-5,8A-DIMETHYL-1-METHYLIDENE-3A,4,5,5A,9,9A-HEXAHYDROAZULENO[6,7-B]FURAN-2,8-DIONE
Chemical Formula
C15H18O4
Molecular Weight
262.3
Appearance
White to off-white Solid
Purity
97%
Solubility
Soluble in DMSO (10 mg/ml) or 100% ethanol.
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An inhibitor of the transcription factor NFκB is a potent antiinflammatory and antineoplastic agent
MDL NUMBER
MFCD01674580
CHEMACX
X1021671-0
INCHI
InChI=1S/C15H18O4/c1-7-6-10-12(8(2)14(18)19-10)13(17)15(3)9(7)4-5-11(15)16/h4-5,7,9-10,12-13,17H,2,6H2,1,3H3/t7-,9+,10-,12-,13+,15+/m1/s1
SMILES
C[C@@H]1C[C@@H]2[C@H]([C@@H]([C@]3([C@H]1C=CC3=O)C)O)C(=C)C(=O)O2
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
UN 3462
PACKING GROUP
II
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial Warning.Toxic.
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
| GHS PICTOGRAMS |  |
|---|---|
| Handling | Store in Tightly Sealed Vial Warning.Toxic. |
| UN #'S | UN 3462 |
| Packing Group | II |
