Hh Signaling Pathway Antagonist

SKU
H-2354
  • CAS:330796-24-2
  • Formula:C23H15ClF4N4O2
  • MW:490.84
  • Appearance:White to off-white Solid
  • Purity:97% by HPLC
Product Name Qty
Hh Signaling Pathway Antagonist
1 mg
$117.25
Cell-permeable. A potent antagonist of the Hedgehog (Hh) signaling pathway (IC= 70 nM).
More Information
Alternate Name/Synonyms
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
SKU
H-2354
CAS #
330796-24-2
Chemical Name
N-[4-Chloro-3-(trifluoromethyl)phenyl]-N’-[[3-(4-fluorophenyl)-3,4-dihydro-4-oxo-2-quinazolinyl]methyl-urea
Chemical Formula
C23H15ClF4N4O2
Molecular Weight
490.84
Appearance
White to off-white Solid
Purity
97% by HPLC
Solubility
Soluble in DMSO
Stability
N/A
Storage Temp
+4°C
THERAPEUTIC AREA
Not Available
USE
It is a potent modulator of Hedgehog (Hh) protein function and a nanomolar hedgehog antagonist
MDL NUMBER
MFCD10567691
CHEMACX
X1823651-2
PubChecm ID
N/A
INCHI
InChI=1S/C23H15ClF4N4O2/c24-18-10-7-14(11-17(18)23(26,27)28)30-22(34)29-12-20-31-19-4-2-1-3-16(19)21(33)32(20)15-8-5-13(25)6-9-15/h1-11H,12H2,(H2,29,30,34)
SMILES
C1=CC=C2C(=C1)C(=O)N(C(=N2)CNC(=O)NC3=CC(=C(C=C3)Cl)C(F)(F)F)C4=CC=C(C=C4)F
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Special Shipping
N/A
E-Guides
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Blog Post
N/A
Citations
N/A
Citations_Hyperlink
N/A
Reference
N/A
Reference Hyperlink
N/A
Additional Images
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Additional Videos
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Hazard Image
N/A
Structure Available (Y/N)
N/A
Promo text for AGS discount
N/A
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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