HPA, HDAC inhibitor
- Appearance:Colorless oil
- Purity:97% by TLC NMR (Conforms)
HPA (96017-59-3) is a histone deacetylase (HDAC) inhibitor, IC50=13 μM. More potent and robust than valproic acid at inducing histone hyperacetylation (600% at 50 μM), HSP70 induction and protection against glutamate excitotoxicity in cultured neurons. Cell permeable.