Turbo3C (HRV 3C) Protease

SKU
H-1192

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1

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Product Name Qty
HRV 3C Protease,Cysteine Protease, PreScission Site
10 mg
$2,010.13
HRV 3C Protease,Cysteine Protease, PreScission Site
1 mg
$261.87

Description

Turbo3C (HRV 3C) Protease (known as human rhinovirus 3C protease) is a recombinant cysteine protease. It cleaves between Gln and Gly in Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro, commonly referred to as the PreScission Site. HRV 3C Protease is a 47 kDa protein with robust activity at 4°C. It also has both GST and His tags, which can be removed by either Ni-chelating or Glutathione (GSH) resin.

Applications

• Used as a therapeutic implication because of its unique protein structure
• Used to achieve high cleavage efficiency without non-specific cleavage of target proteins
• Used for the biochemical and structural characterization conducted on HRV 3C protease along with the development of 3C protease inhibitors

 

More Information
Alternate Name/Synonyms
HRV 3C Protease, Cysteine Protease, PreScission Site
SKU
H-1192
CAS #
N/A
Chemical Name
N/A
Chemical Formula
N/A
Molecular Weight
N/A
Appearance
N/A
Purity
N/A
Solubility
N/A
Melting Point
N/A
Preparation
It is recommended to test the HRV3C Protease cleavage with protease-to-target protein ratio of 1:100 (w/w) in the buffer suitable for the target protein at 4°C overnight, with the target protein concentration at or below 1 mg/ml. Under this condition, > 9
Storage Temp
Store at -20°C. HRV3C is stable at room temperature for up to 2 weeks.
THERAPEUTIC AREA
Not Applicable
USE
Human rhinovirus 3C protease (HRV3C Protease) is a cysteine protease that recognizes the cleavage site of Leu-Glu-Val-Leu-Phe-Gln-Gly-Pro, commonly referred to as the PreScission Site. It cleaves between Gln and Gly. The recombinant Turbo3C Protease is a restriction grade HRV3C protease that has robust activity at 4oC and high specific activity. Turbo3C Protease is a 47 kDa protein with both GST and His tags so it can be removed by either Ni chelating or Glutathione (GSH) resin.
Merck Index
N/A
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
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