Hydrolyzed Fumonisin B2

SKU
F-1025
  • CAS:147985-10-2
  • Formula:C22H47NO4
  • MW:389.6 kDa
  • Appearance:Yellow film
  • Purity:≥97% ; detection by ELSD

Starting at $804.23

Product Name Qty
Hydrolyzed Fumonisin B2
1 mg
$804.23
Hydrolyzed Fumonisin B2
50 mg
$23,451.37
Hydrolyzed Fumonisin B2
5 mg
$3,216.92
Hydrolyzed Fumonisin B2
100 mg
$42,212.46
Hydrolyzed Fumonisin B2
10 mg
$5,790.46
Hydrolyzed Fumonisin B2
25 mg
$13,028.54

Fumonisins are a group of mycotoxins derived from species of the fungus Fusarium. Fumonisin B2 is a carcinogenic, toxic secondary metabolite that inhibits sphingosine acyltransferase. The alteration in sphingolipid metabolism leads to apoptosis, causing hepatoxicity and nephrotoxicity in animals.  Fumonisin B2 is more cytotoxic than its structural analog, fumonisin B1. FB2 is isolated from the fungi Fusarium moniliforme (aka Fusarium verticilliodies) and is often found as a contaminant in corn and other grains.

The removal of propane-1,2,3-tricarboxylic acid side chains produces hydrolyzed fumonisins, including hydrolyzed fumonisin B2. Hydrolyzed fumonisins may be found in alkaline cooked foods such as masa and tortillas. These forms have been found to more weakly inhibit sphingosine acyltransferase than their non-hydrolyzed form.

 

 

More Information
Alternate Name/Synonyms
HFB2, Fumonisin AP2, AP2 metabolite, AP2, Fumonisin HB2, Hydrolyzed Fumonisin B2
SKU
F-1025
CAS #
147985-10-2
Chemical Formula
C22H47NO4
Molecular Weight
389.6 kDa
Appearance
Yellow film
Purity
≥97% ; detection by ELSD
Solubility
Methanol: clear colorless solution at 10 mg/mL
Storage Temp
Store in a freezer upon arrival, at -10°C to -25°C
USE
Disruption of sphingolipid metabolism
Handling
Avoid contact with skin, eyes or clothing.
Hazard Image
Yes
GHS PICTOGRAMS
Handling Avoid contact with skin, eyes or clothing.
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