IC87114

SKU
I-2356
  • CAS:371242-69-2
  • Formula:C22H19N7O
  • MW:397.43
  • Appearance:White to off-white Solid
  • Purity:95% by HPLC
Product Name Qty
IC87114
1 mg
$222.12
Cell-permeable. A potent, ATP-competitive and selective inhibitor of PI 3-K isoform p110 (IC= 60 nM). Inhibits p110 and p110 only at higher concentrations (1 M). IC87114 does not inhibit other PIK-related kinases such as ATM, ATR, DNA-PK, and mTOR even at concentrations up to 100 M.
More Information
Alternate Name/Synonyms
2-[6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
SKU
I-2356
CAS #
371242-69-2
Chemical Name
2-[6-Amino-9H-purin-9-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone
Chemical Formula
C22H19N7O
Molecular Weight
397.43
Appearance
White to off-white Solid
Purity
95% by HPLC
Solubility
Soluble in DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
IC-87114 selectively inhibits PI3K inhibitor with action against fMLP-PIP3.
MDL NUMBER
MFCD09970845
CHEMACX
X1812304-1
INCHI
InChI=1S/C22H19N7O/c1-13-6-3-4-9-16(13)29-17(27-15-8-5-7-14(2)18(15)22(29)30)10-28-12-26-19-20(23)24-11-25-21(19)28/h3-9,11-12H,10H2,1-2H3,(H2,23,24,25)
SMILES
CC1=C2C(=CC=C1)N=C(N(C2=O)C3=CC=CC=C3C)CN4C=NC5=C(N=CN=C54)N
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
Handling Protect from air and light
UN #'S Not Applicable
Packing Group Not Applicable
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