Indirubin-3'-monoxime

SKU
I-1076
  • CAS:160807-49-8
  • Formula:C16H11N3O2
  • MW:277.3
  • Appearance:Dark Red Powder
  • Purity:98%

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Product Name Qty
Indirubin-3'-monoxime
1 mg
$85.43
Indirubin-3'-monoxime
5 mg
$341.72

Selective and strong inhibitor of cyclin-dependent kinases. Inhibits the proliferation of a large range of cells, mainly through arresting the cells in the G2/M phase of the cell cycle.

More Information
SKU
I-1076
CAS #
160807-49-8
Chemical Name
3-[1,3-DIHYDRO-3-(HYDROXYIMINO)-2H-INDOL-2-YLIDENE]-1,3-DIHYDRO-2H-INDOL-2-ONE
Chemical Formula
C16H11N3O2
Molecular Weight
277.3
Appearance
Dark Red Powder
Purity
98%
Solubility
Soluble in DMSO (>25 mg/ml), 100% ethanol (12 mg/ml), and DMF
Melting Point
247-249 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Indirubin-3'-monoxime is a potent inhibitor of GSK-3B
MDL NUMBER
MFCD02683594
CHEMACX
X1342374-2
INCHI
InChI=1S/C16H11N3O2/c20-16-13(9-5-1-3-7-11(9)18-16)15-14(19-21)10-6-2-4-8-12(10)17-15/h1-8,17,21H,(H,18,20)/b15-13-,19-14+
SMILES
C1=CC=C2C(=C1)/C(=C/3C(=NO)C4=CC=CC=C4N3)/C(=O)N2
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial
Citations
PATHOGENESIS AND IMMUNITY: Vpr Cytopathicity Independent of G2/M Cell Cycle Arrest in Human Immunodeficiency Virus Type 1-Infected CD4+ T Cells Diane L. Bolton and Michael J. Lenardo J. Virol., Sep 2007; 81: 8878 - 8890.
Citations_Hyperlink
http://jvi.asm.org/cgi/reprint/81/17/8878
Certificate of Analysis 1
Handling Store in Tightly Sealed Vial
UN #'S Not Applicable
Packing Group Not Applicable
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