- Appearance:Light yellow Solid
- Purity:97% by HPLC
Isozyme -selective-Akt inhibitor is a cell-permeable, potent and selective inhibitor of Akt1/Akt2 activity (IC = 58 nM (Akt1), 210 nM (Akt2) and 2.12 M (Akt3) in vitro kinase assays. The inhibition appears to be pleckstrin homology (PH) domain-dependent. It does not exhibit any inhibitory effect against PH domain-lacking Akt's, or other closely related AGC family kinases, PKA, PKC, and SGK, even at concentrations (50 M).
|Handling||Protect from air and moisture|
|UN #'S||Not Applicable|
|Packing Group||Not Applicable|