Ivermectin B1a monosaccharide

SKU
I-2577
  • CAS:71837-27-9
  • Formula:C41H62O11
  • MW:730.9 Da
  • Appearance:White solid
  • Purity:>99% by HPLC

Starting at $355.39

Product Name Qty
Ivermectin B1a monosaccharide
1 mg
$355.39
Ivermectin B1a monosaccharide
5 mg
$1,243.86

Description

Ivermectin monosaccharide is a semi-synthetic produced by selective hydrolysis of the terminal saccharide unit of ivermectin. Ivermectin monosaccharide is a potent inhibitor of nematode larval development, but is devoid of paralytic activity. The monosaccharide is used as a sensitive probe for the detection of some types of ivermectin resistance.

References

• Ivermectin, a new broad-spectrum antiparasitic agent

• Detection of resistance to ivermectin in haemonchus contortus

Not for human therapeutic use or for medicinal purposes. For research applications only.

More Information
Alternate Name/Synonyms
Dihydroavermectin B1 monosaccharide; Ivermectin B1 monosaccharide
SKU
I-2577
CAS #
71837-27-9
Chemical Formula
C41H62O11
Molecular Weight
730.9 Da
Appearance
White solid
Purity
>99% by HPLC
Solubility
Soluble in ethanol, methanol, DMF or DMSO. Poor water solubility.
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
Used as a sensitive probe for the detection of some types of ivermectin resistance
MDL NUMBER
MFCD14635438
INCHI
InChI=1S/C41H62O11/c1-9-22(2)37-25(5)15-16-40(52-37)20-30-18-29(51-40)14-13-24(4)36(50-33-19-32(46-8)35(43)27(7)48-33)23(3)11-10-12-28-21-47-38-34(42)26(6)17-31(39(44)49-30)41(28,38)45/h10-13,17,22-23,25,27,29-38,42-43,45H,9,14-16,18-21H2,1-8H3/b11-10+,24-13+,28-12+/t22-,23-,25-,27-,29+,30-,31-,32-,33-,34+,35-,36-,37+,38+,40+,41?/m0/s1
SMILES
CC[C@H](C)[C@@H]1[C@H](CC[C@@]2(O1)C[C@@H]3C[C@H](O2)C/C=C(/[C@H]([C@H](/C=C/C=C/4\CO[C@H]5C4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H]([C@H]([C@@H](O6)C)O)OC)\C)C
Handling
Avoid prolonged or repeated exposure.
Handling Avoid prolonged or repeated exposure.
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