Inhibitor of Wnt Production-2
686770-61-6
466.6
C22H18N4O3S3
DMF, DMSO
-20°C
IWP-2 is a cell-permeable inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC= 27 nM) by inhibition of the O-acyltransferase Porcn. Porcn is a member of the membrane-bound O-acyltransferase (MBOAT) family, which adds a palmitoyl group to Wnt proteins that is essential to their signaling ability and is required for Wnt secretion.
0.1 lbs
Research or further manufacturing use only, not for food or drug use.
