JAK Inhibitor I

SKU
J-1130
  • CAS:457081-03-7
  • Formula:C18H16FN3O
  • MW:309.3
  • Appearance:Off-White Solid
  • Purity:98%

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Product Name Qty
JAK Inhibitor I
500 ug
$120.24
JAK Inhibitor I
1 mg
$214.33

 A potent, cell-permeable, and ATP-competitive inhibitor of Janus protein tyrosine kinases (JAKs).

More Information
Alternate Name/Synonyms
CMP 6, Pyridone 6, Janus-associated kinase inhibitor I, 2-(1,1- dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5- f]isoquinolin-7-one
SKU
J-1130
CAS #
457081-03-7
Chemical Name
2-(1,1- dimethylethyl)-9-fluoro-1,6-dihydro-7H-benz[h]imidazo[4,5- f]isoquinolin-7-one
Chemical Formula
C18H16FN3O
Molecular Weight
309.3
Appearance
Off-White Solid
Purity
98%
Solubility
Soluble in DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
An inhibitor of JAK1, JAK2, and JAK3
MDL NUMBER
MFCD17019334
CHEMACX
X1881054-3
INCHI
InChI=1S/C18H16FN3O/c1-18(2,3)17-21-14-10-5-4-9(19)8-12(10)13-11(15(14)22-17)6-7-20-16(13)23/h4-8H,1-3H3,(H,20,23)(H,21,22)
SMILES
CC(C)(C)c1[nH]c2c3cc[nH]c(=O)c3c4cc(ccc4c2n1)F
Handling
Protect from Light Packaged under inert gas.
Handling Protect from Light Packaged under inert gas.
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