JK 184

SKU
J-2367
  • CAS:315703-52-7
  • Formula:C19H18N4OS
  • MW:350.44
  • Appearance:Beige Solid
  • Purity:98% by HPLC
Product Name Qty
JK 184
1 mg
$111.64
An imidazopyridine derivative that acts as a potent downstream antagonist of Hedgehog(Hh) signaling pathway. JK184 functions by inhibiting class IV alcohol dehydrogenase (Aldh7) (IC= 210 nM).
More Information
Alternate Name/Synonyms
N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-y l)-2-thiazolamine
SKU
J-2367
CAS #
315703-52-7
Chemical Name
N-(4-Ethoxyphenyl)-4-(2-methylimidazo[1,2-a]pyridin-3-y l)-2-thiazolamine
Chemical Formula
C19H18N4OS
Molecular Weight
350.44
Appearance
Beige Solid
Purity
98% by HPLC
Solubility
Soluble in DMSO (100 mM) and Ethanol (25 mM)
Melting Point
235.63 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
Potent Hedgehog signaling inhibitor.JK 184 exhibits antiproliferative activity in a range of cancer cell
MDL NUMBER
MFCD01044465
CHEMACX
X1763998-0
INCHI
InChI=1S/C19H18N4OS/c1-3-24-15-9-7-14(8-10-15)21-19-22-16(12-25-19)18-13(2)20-17-6-4-5-11-23(17)18/h4-12H,3H2,1-2H3,(H,21,22)
SMILES
CCOc1ccc(cc1)Nc2nc(cs2)c3c(nc4n3cccc4)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
HandlingProtect from air and light
UN #'SNot Applicable
Packing GroupNot Applicable
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