L-156602

SKU
L-2519
  • CAS:125528-51-5
  • Formula:C38H64N8O13
  • MW:840.5
  • Appearance:White solid off white light tan
  • Purity:>95% by HPLC
Product Name Qty
L-156602
0.5 mg
$197.60
L-156602
2.5 mg
$688.78
*Please inquire the availability for this product. L 156602 is a cyclic hexapeptide isolated from a strain of Streptomyces by researchers at Merck USA and reported in 1991. L 156602 belongs to the aurantimycin class and, like other members, is active against Gram positive bacteria. L 156602 was foremost discovered as a competitive binding inhibitor of the inflammatory peptide, C5a, to cell surface receptors on macrophages. In vivo, L 156602 profoundly suppresses footpad edema induced by concanavalin A and completely suppresses the infiltration of mononuclear leukocytes and neutrophils into the site of inflammation.
More Information
Alternate Name/Synonyms
Antibiotic L 16602
SKU
L-2519
CAS #
125528-51-5
Chemical Formula
C38H64N8O13
Molecular Weight
840.5
Appearance
White solid off white light tan
Purity
>95% by HPLC
THERAPEUTIC AREA
Infectious Diseases
USE
L 156602 is antibiotic belongs to the aurantimycin class and active against Gram positive bacteria
INCHI
InChI=1S/C38H64N8O13/c1-9-21(4)18-25-14-15-38(55,59-24(25)7)37(8,54)36(53)42-29-30(20(2)3)58-35(52)23(6)46(57)32(49)26-12-10-16-40-43(26)28(47)19-39-31(48)22(5)45(56)33(50)27-13-11-17-41-44(27)34(29)51/h20-27,29-30,40-41,54-57H,9-19H2,1-8H3,(H,39,48)(H,42,53)
SMILES
CCC(C)CC1CCC(OC1C)(C(C)(C(=O)NC2C(OC(=O)C(N(C(=O)C3CCCNN3C(=O)CNC(=O)C(N(C(=O)C4CCCNN4C2=O)O)C)O)C)C(C)C)O)O
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