L-NMMA

SKU
M-1014
  • CAS:53308-83-1
  • Formula:C7H16N4O2 • CH3COOH
  • MW:248.3 Da
  • Appearance:White powder
  • Purity:≥99% (TLC)

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Product Name Qty
L-NMMA
100 mg
$217.76
L-NMMA
25 mg
$67.00
A widely utilized inhibitor of Nitric Oxide Synthase (NOS).
More Information
Alternate Name/Synonyms
L-NMMA (Acetate); L-NMMA monoacetate; NG-Monomethyl-L-arginine monoacetate; L-NG-monomethyl Arginine acetate; Tilarginine Acetate; Nomega-Me-L-Arg
SKU
M-1014
CAS #
53308-83-1
Chemical Name
acetic acid;(2S)-2-amino-5-[(N'-methylcarbamimidoyl)amino]pentanoic acid
Chemical Formula
C7H16N4O2 • CH3COOH
Molecular Weight
248.3 Da
Appearance
White powder
Purity
≥99% (TLC)
Solubility
Soluble in water (10 mg/mL).
Melting Point
182-192 °C
Storage Temp
-20°C, desiccated
THERAPEUTIC AREA
Not Available
USE
L-NMMA has been used as an inhibitor of nitric oxide synthase (NOS) in wound healing studies in injured mice and as an inhibitor of nitric oxide synthase (NOS) to study nitric oxide (NO) immunosuppressive effect of murine stem cells. It is also used as an inhibitor to monitor NO levels in hemocytes respiratory burst assay.
MDL NUMBER
MFCD00069311
CHEMACX
X1093283-9
INCHI
InChI=1S/C7H16N4O2.C2H4O2/c1-10-7(9)11-4-2-3-5(8)6(12)13;1-2(3)4/h5H,2-4,8H2,1H3,(H,12,13)(H3,9,10,11);1H3,(H,3,4)/t5-;/m0./s1
SMILES
CC(=O)O.CNC(=N)NCCC[C@@H](C(=O)O)N
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.
Citations
Lysozyme, a mediator of sepsis, impairs the cardiac neural adrenergic response by nonendothelial release of NO and inhibitory G protein signaling Steven N. Mink, Zhao-Qin Cheng, Ratna Bose, Hans Jacobs, Krika Kasian, Diane E. Roberts, Luis E. Santos-Martinez, and R. Bruce Light Am J Physiol Heart Circ Physiol, Nov 2007; 293: H3140 - H3149.
Citations_Hyperlink
http://ajpheart.physiology.org/cgi/reprint/293/5/H3140
Certificate of Analysis 1
Certificate of Analysis 2
Certificate of Analysis 3
Handling Provide appropriate exhaust ventilation at places where dust is formed.Normal measures for preventive fire protection.
UN #'S Not Applicable
Packing Group Not Applicable
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