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L-Quisqualic Acid, 1 MG

Price$ 60.50
  • SKU: Q-1000-1MG
  • Pack Size: 1 MG
Quantity
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+

Quisqualic Acid; Quisqualate; 3-(3,5-Dioxo-1,2,4- oxadiazolidin-2-yl)-L-alanine; β-(3,5-Dioxo-1,2,4- oxadiazolidin-2-yl)-L-alanine; L-(+)-α-Amino-3,5-dioxo1,2,4-oxadiazolidine-2- propanoic acid

52809-07-1

189.13

C5H7N3O5

Water, NaOH

2-8°C


L-Quisqualic Acid is one of the most potent AMPA receptor agonists, causing excitotoxicity -- a process in which nerve cells are killed or damaged due to the overstimulation of neurotransmitters. It is also believed to mimic the excitatory neurotransmitter L-glutamic acid, which is studied in relation to insect neuromuscular function and the mammalian central nervous system.


Commonly used in neuroscience to deliberately kill brain and/or spinal cord neurons, L-Quisqualic Acid is also used to sensitize neurons to depolarization within the hippocampus (known as the "quis effect") -- which is the movement of a cell membrane's potential, making it slightly more positive.

 
 

0.1 lbs



Research or further manufacturing use only, not for food or drug use.

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