- MW:189.13 Da
- Appearance:White to off-white powder
L-Quisqualic Acid is one of the most potent AMPA receptor agonists, causing excitotoxicity -- a process in which nerve cells are killed or damaged due to the overstimulation of neurotransmitters. It is also believed to mimic the excitatory neurotransmitter L-glutamic acid, which is studied in relation to insect neuromuscular function and the mammalian central nervous system.
Commonly used in neuroscience to deliberately kill brain and/or spinal cord neurons, L-Quisqualic Acid is also used to sensitize neurons to depolarization within the hippocampus (known as the "quis effect") -- which is the movement of a cell membrane's potential, making it slightly more positive.
|Handling||Whenever possible, prepare and use solutions on the same day. If stock solutions are made in advance, they can be stored at -20°C for up to one month. Ensure adequate ventilation.|