Leflunomide

SKU
L-2372
  • CAS:75706-12-6
  • Formula:C12H9F3N2O2
  • MW:270.21
  • Appearance:White to off-white Solid
  • Purity:98% by HPLC

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Product Name Qty
Leflunomide
50 mg
$194.78
Leflunomide
10 mg
$70.34
Cell-permeable. An immunosuppressive agent. Inhibits T and B cell responses in vivo. Inhibitor of tyrosine phosphorylation (tyrosine kinase inhibitor), of dihydroorotate dehydrogenase, an enzyme for de novo pyrimidine synthesis, of TNFdependent NF-B activation, and of COX-2. The physiological activity of leflunomide is attributed mainly to its metabolite A77 1726.
More Information
Alternate Name/Synonyms
HWA486
SKU
L-2372
CAS #
75706-12-6
Chemical Name
5-Methylisoxazole-4-(4-trifluoromethylcarboxanilide), N-(4-Trifluoromethylphenyl)-5-methylisoxazol-4-carboxamide
Chemical Formula
C12H9F3N2O2
Molecular Weight
270.21
Appearance
White to off-white Solid
Purity
98% by HPLC
Solubility
DMSO (100 mM) or Ethanol (100 mM)
Stability
N/A
Melting Point
166.5 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Autoimmune Diseases
USE
Leflunomide is an immunosuppressive drug that inhibits T and B cell responses.
MDL NUMBER
MFCD00867593
CHEMACX
X1063791-7
INCHI
InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18)
SMILES
Cc1c(cno1)C(=O)Nc2ccc(cc2)C(F)(F)F
Peptide sequence
Not Applicable
RTECS
NY2354200
UN #'S
UN 2811
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Protect from light and air
Certificate of Analysis 1
Promo text for AGS discount
N/A
GHS PICTOGRAMS
Handling Protect from light and air
UN #'S UN 2811
Packing Group III
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