Lexithromycin

SKU
L-2551
  • CAS:53066-26-5
  • Formula:C38H70N2O13
  • MW:763
  • Appearance:White solid
  • Purity:>98% by HPLC
Product Name Qty
Lexithromycin
5 mg
$187.61
Lexithromycin
25 mg
$656.05
*Please inquire the availability for this product. Lexithromycin is an early semi-synthetic erythromycin, prepared by reaction of the 9-keto moiety to methyl oxime. The structural change improves the pH stability profile and hydrophobicity of lexithromycin for better in vivo absorption. This same rationale was used to greater effect with roxithromycin and, as a result, lexithromycin was quickly superseded and has not been not extensively studied. Like all erythromycins, lexithromycin shows broad spectrum antibacterial activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis.
More Information
Alternate Name/Synonyms
Erythromycin A 9-methoxime, Wy 48314
SKU
L-2551
CAS #
53066-26-5
Chemical Formula
C38H70N2O13
Molecular Weight
763
Appearance
White solid
Purity
>98% by HPLC
Storage Temp
-20°C
THERAPEUTIC AREA
Infectious Diseases
USE
lexithromycin shows broad spectrum antibacterial activity
MDL NUMBER
MFCD00864895
INCHI
InChI=1S/C38H70N2O13/c1-15-26-38(10,46)31(42)21(4)28(39-48-14)19(2)17-36(8,45)33(53-35-29(41)25(40(11)12)16-20(3)49-35)22(5)30(23(6)34(44)51-26)52-27-18-37(9,47-13)32(43)24(7)50-27/h19-27,29-33,35,41-43,45-46H,15-18H2,1-14H3/b39-28+/t19-,20-,21+,22+,23-,24+,25+,26-,27+,29-,30+,31-,32+,33-,35+,36-,37-,38-/m1/s1
SMILES
CC[C@@H]1[C@@]([C@@H]([C@H](/C(=N/OC)/[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)O)(C)O
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