Manumycin A, Streptomyces parvulus

SKU
M-1052
  • CAS:52665-74-4
  • Formula:C31H38N2O7
  • MW:550.7
  • Appearance:Yellow Solid
  • Purity:96% (HPLC)
Product Name Qty
Manumycin A, Streptomyces parvulus
1 mg
$176.59
Manumycin A, Streptomyces parvulus
5 mg
$678.80
A potent and selective inhibitor of Ras farnesyltransferase.
More Information
SKU
M-1052
CAS #
52665-74-4
Chemical Name
(2E,4E,6R)-N-[(1S,5S,6R)-5-HYDROXY-5-((1E,3E,5E)-7-[(2-HYDROXY-5-OXO-1-CYCLOPENTEN-1-YL)AMINO]-7-OXO-1,3,5-HEPTATRIEN-1-YL)-2-OXO-7-OXABICYCLO[4.1.0]HEPT-3-EN-3-YL]-2,4,6-TRIMETHYL-2,4-DECADIENAMIDE
Chemical Formula
C31H38N2O7
Molecular Weight
550.7
Appearance
Yellow Solid
Purity
96% (HPLC)
Solubility
Soluble in 100% ethanol; slightly soluble in chloroform.
Storage Temp
+4°C Short term.-20°C long term
THERAPEUTIC AREA
Oncological Disorders
USE
A potent and selective inhibitor of Ras farnesyltransferasein cancer
MDL NUMBER
MFCD00920782
CHEMACX
X1093234-6
INCHI
InChI=1S/C31H38N2O7/c1-5-6-11-19(2)16-20(3)17-21(4)30(38)32-22-18-31(39,29-28(40-29)27(22)37)15-10-8-7-9-12-25(36)33-26-23(34)13-14-24(26)35/h7-10,12,15-19,28-29,34,39H,5-6,11,13-14H2,1-4H3,(H,32,38)(H,33,36)/b8-7+,12-9+,15-10+,20-16+,21-17+/t19-,28-,29-,31+/m1/s1
SMILES
CCCC[C@@H](C)/C=C(C)/C=C(C)/C(=O)NC1=C[C@]([C@H]2[C@@H](C1=O)O2)(/C=C/C=C/C=C/C(=O)NC3=C(CCC3=O)O)O
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Store in Tightly Sealed Vial Protect from Light
Certificate of Analysis 1
HandlingStore in Tightly Sealed Vial Protect from Light
UN #'SNot Applicable
Packing GroupNot Applicable
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