MES Monohydrate
SKU
M-1219
- CAS:145224-94-8
- Formula:C6H13NO4S • H2Oc
- MW:213.24 Da
- Appearance:White crystalline powder
- Purity:≥99.0%
SDS
CofA
Description
Biological buffer with a pKa of 6.15 (20°C). Useful in plant tissue culture. It is a zwitterionic acid.
• pKa (20°C): 6.15
• pH range: 5.5 - 6.7
• Chloride (Cl): ≤0.01%
• Heavy Metals: ≤0.0010%
• Insoluble Matter: Pass (Filter Test)
• Iron: ≤0.0010%
• Loss on Drying: 7.0 - 10.0%
• pH: 2.5 - 4.0
• pKa @20°C: 6.02 - 6.25
• Solubility (10% solution in water): Clear
• UV Absorbance 250nm in 10% water: ≤0.05
Applications
• used for cell culture media
• as a running buffer in electrophoresis
• for protein purification in chromatography
• buffered culture media for bacteria/yeast
More Information
Alternate Name/Synonyms
2-(N-Morpholino)ethanesulfonic acid; 4-Morpholineethanesulfonic acid monohydrate; MES Hydrate Buffer
SKU
M-1219
CAS #
145224-94-8
Chemical Name
2-morpholin-4-ylethanesulfonic acid;hydrate
Chemical Formula
C6H13NO4S • H2Oc
Molecular Weight
213.24 Da
Appearance
White crystalline powder
Purity
≥99.0%
Solubility
Water (10% in H2O)
Melting Point
316 °C
Preparation
N/A
Storage Temp
Room temperature
THERAPEUTIC AREA
Not Available
USE
MES is a biological buffer often referred to as a “Good’s” buffer .The pKa of MES is 5.96 which makes MES an ideal candidate for cell culture media and protein based buffer formulations to maintain a stable environment in solution. MES is considered to be non-toxic to culture cell lines, highly water soluble and provides high solution clarity. It is used in cell culture media, biopharmaceutical buffer formulations (both upstream and downstream), and diagnostic reagents. MES based buffers are used in purification bioprocesses of antibodies, peptides, proteins, blood components and growth factors.
Merck Index
N/A
MDL NUMBER
MFCD00006181
CHEMACX
X1009953-3
INCHI
MIIIXQJBDGSIKL-UHFFFAOYSA-N
SMILES
C1COCCN1CCS(=O)(=O)O
Peptide sequence
Not Applicable
GHS Pictograms
9
RTECS
QE3479500
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.
msds 1
/media/upload/pdf/M-1219, MES Buffer, SDS, diamond format.pdf
Certificate of Analysis 1
/media/upload/pdf/M-1219, J1276.pdf
Certificate of Analysis 2
/media/upload/pdf/M-1219, H1250B.pdf
Certificate of Analysis 3
/media/upload/pdf/M-1219, H1250A.pdf
Spec
| GHS PICTOGRAMS |
|
|---|---|
| Handling | Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust. |
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |
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