MIF-Antagonist, ISO-1

SKU

M-2379

CAS:478336-92-4
Formula:C₁₂H₁₃NO₄
MW:235.24
Appearance:Off-White Solid
Purity:98% by HPLC

SDS

CofA

Product Name	Qty
MIF-Antagonist, ISO-1 5 mg $108.21

Details

Cell-permeable. A macrophage migration inhibitory factor (MIF) antagonist. ISO-1 inhibits MIF pro-inflammatory activities by targeting MIF tautomerase activity. Also inhibits tumor necrosis factor (TNF) release from macrophages isolated from LPS- treated wild type mice but has no effect on cytokine release from MIF deficient macrophages.

Specifications

More Information

Alternate Name/Synonyms

(S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester

SKU

M-2379

CAS #

478336-92-4

Chemical Name

(S,R)-3-(4-Hydroxyphenyl)-4,5-dihydro-5-isoxazole acetic acid, methyl ester

Chemical Formula

C₁₂H₁₃NO₄

Molecular Weight

235.24

Appearance

Off-White Solid

Purity

98% by HPLC

Solubility

Soluble in DMSO (~25 mg/ml)

Stability

N/A

Melting Point

133.69 °C

Storage Temp

-20°C

THERAPEUTIC AREA

Endocrinological Disorders

USE

MIF Antagonist, ISO-1 has been shown to exhibit antidiabetogenic properties in immunoinflammatory diabetic

MDL NUMBER

MFCD22376813

CHEMACX

X4983373-6

PubChecm ID

N/A

INCHI

InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,14H,6-7H2,1H3

SMILES

COC(=O)CC1CC(=NO1)c2ccc(cc2)O

Handling

Protect from air and light

Special Shipping

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Citations

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Reference

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Safety

GHS PICTOGRAMS
Handling	Protect from air and light

Citations