Milbemycin D

SKU
M-2593
  • CAS:77855-81-3
  • Formula:C33H48O7
  • MW:556.7 Da
  • Appearance:White solid
  • Purity:>95% by HPLC

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Product Name Qty
Milbemycin D
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Description

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin D is a minor member of a group of analogues containing a 25-isopropyl substituent. Milbemycin D is a highly selective and potent nematocide and insecticide. Like the closely related avermectin, milbemycins are thought to act by opening glutamate sensitive chloride channels.

More Information
Alternate Name/Synonyms
Antibiotic B 41D; Milbemycin
SKU
M-2593
CAS #
77855-81-3
Chemical Name
(1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21R,24S)-21,24-dihydroxy-5',11,13,22-tetramethyl-6'-propan-2-ylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one
Chemical Formula
C33H48O7
Molecular Weight
556.7 Da
Appearance
White solid
Purity
>95% by HPLC
Solubility
ethanol, methanol, DMF or DMSO
Storage Temp
-20°C
USE
A potent nematocide and insecticide
MDL NUMBER
MFCD01939747
INCHI
InChI=1S/C33H48O7/c1-19(2)29-22(5)12-13-32(40-29)17-26-16-25(39-32)11-10-21(4)14-20(3)8-7-9-24-18-37-30-28(34)23(6)15-27(31(35)38-26)33(24,30)36/h7-10,15,19-20,22,25-30,34,36H,11-14,16-18H2,1-6H3/b8-7+,21-10+,24-9+/t20-,22-,25+,26-,27-,28+,29+,30+,32+,33+/m0/s1
SMILES
C[C@H]1CC[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/C[C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)\C)O[C@@H]1C(C)C
Handling
Handle in accordance with good industrial hygiene and safety practice
Handling Handle in accordance with good industrial hygiene and safety practice
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