Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore

SKU
M-3325
  • Formula:C35H31BrN3O8P
  • MW:732.51
  • Appearance:Pale yellow solid
  • Purity:98% by TLC NMR (Conforms)
Product Name Qty
Mito-Photo-DNP, Mitochondria specific, photo-activated protonophore
5 mg
$256.19

Mito-Photo-DNP is a mitochondria-targeted, photo-activated protonophore. This novel tool consists of three structural units, a caged protonophore, a photocleavable linker coupled to a triphenylphosphonium moiety which confers selective uptake by the mitochondria. Cells are treated with Mito-Photo-DNP at 200 nM and irradiated with UV light at 355 nm. Mito-Photo-DNP can be employed for selective uncoupling of either individual or a small number of mitochondria within a cell when used with fluorescence imaging.  

Application:

  • Used for research studies, to manipulate mitochondrial function;
  • To release bioactive molecules, pharmacophores, or toxins to mitochondria with tissue, cell, or mitochondrion specificity.
More Information
SKU
M-3325
Chemical Name
(4-(3-((2,4-Dinitrophenoxy)methyl)-4-nitrophenoxy)butyl)triphenylphosphonium
Chemical Formula
C35H31BrN3O8P
Molecular Weight
732.51
Appearance
Pale yellow solid
Purity
98% by TLC NMR (Conforms)
Solubility
Soluble in DMSO (up to 60 mg/ml) or in Ethanol (up to 30 mg/ml).
Stability
Stable for 3 years as supplied. Solutions in DMSO or Ethanol may be stored at -20°C for up to 3 months.
Storage Temp
-20°C
USE
Used to manipulate mitochondrial function; to release bioactive molecules, pharmacophores, or toxins to mitochondria with tissue, cell, or mitochondrion specificity.
Hazard Image
Yes
Certificate of Analysis 1
Promo text for AGS discount
N/A
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