SDS
CofA
MK-571.Na is a leukotriene receptor ligand. MK-571.Na is a potent, selective, orally active leukotriene D4 antagonist. Ki=2.1 nM forinhibition of [3H]-LTD4 binding to human lung membranes. Competitively antagonizes contractions of guinea pig trachea and ileum and human trachea induced by LTD4. MK-571.Na blocks LTD4 and ascaris-induced bronchoconstriction in conscious squirrel monkeys.
* Listed below are a few published articles demonstrating the use of our. Inquire for a full list of references.
- Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11). Jenny M. Pedersen et al, Toxicol. Sci. (2013) doi: 10.1093,197
More Information
Alternate Name/Synonyms
MK571, MK571 Na
SKU
M-1177
CAS #
115104-28-4
Chemical Formula
C26H26CIN2O3S2‚·Na
Molecular Weight
537.0
Appearance
Light yellow solid
Purity
≥97%
Solubility
Soluble in water
Storage Temp
-20°C
Merck Index
Merck Index: 13.6236.2001
Citations
RESEARCH ARTICLE:
Early Identification of Clinically Relevant Drug Interactions With the Human Bile Salt Export Pump (BSEP/ABCB11)
Jenny M. Pedersen, Pär Matsson, Christel A. S. Bergström, Janet Hoogstraate, Agneta Norén, Edward L. LeCluyse, and Per Artursson
Toxicol. Sci., Dec 2013; 136: 328 - 343.
Citations_Hyperlink
http://toxsci.oxfordjournals.org/content/136/2/328.full.pdf+html
Certificate of Analysis 1
Certificate of Analysis 2
