Monastrol

SKU
M-1116
  • Formula:C14H16N2O3S
  • MW:292.4
  • Appearance:White Solid
  • Purity:95%
Product Name Qty
Monastrol
5 mg
$134.01
Monastrol
25 mg
$541.62
Monastrol
1 mg
$67.00
Monastrol is a potent, cell permeable non-tubulin-interacting mitosis inhibitor. Monastrolblocks mitosis (IC= 14 M) by binding to the mitotic kinesin Eg5, a motor protein required for spindle bipolarity.Seeking published researchers utilizing our Monastrol product? Hit the link for the full paper.MCAK activity at microtubule tips regulates spindle microtubule length to promote robust kinetochore attachment.Functional Analysis of Human Microtubule-based Motor Proteins, the Kinesins and Dyneins, in Mitosis/Cytokinesis Using RNA Interference.
More Information
Alternate Name/Synonyms
4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic acid ethyl ester
SKU
M-1116
Chemical Name
4-(3-Hydroxyphenyl)-6-methyl-2-thioxo-1,2,3,4-tetrahydro-4H-pyrimidin-5-carboxylic acid ethyl ester
Chemical Formula
C14H16N2O3S
Molecular Weight
292.4
Appearance
White Solid
Purity
95%
Solubility
Soluble in 100% ethanol and DMSO.
Melting Point
184 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Not Available
USE
Not Available
MDL NUMBER
MFCD00813077
CHEMACX
X1342912-2
INCHI
InChI=1S/C14H16N2O3S/c1-3-19-13(18)11-8(2)15-14(20)16-12(11)9-5-4-6-10(17)7-9/h4-7,12,17H,3H2,1-2H3,(H2,15,16,20)
SMILES
CCOC(=O)C1=C(NC(=S)NC1c2cccc(c2)O)C
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from Light
Certificate of Analysis 1
Certificate of Analysis 2
Handling Protect from Light
UN #'S Not Applicable
Packing Group Not Applicable
To Top