Entinostat

SKU
M-2358
  • CAS:209783-80-2
  • Formula:C21H20N4O3
  • MW:376.41
  • Appearance:Crystalline Solid
  • Purity:99% by HPLC

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Product Name Qty
Entinostat
25 mg
$235.57
Entinostat
5 mg
$81.51

Preferentially inhibits HDAC1 (IC= 300 nM) over HDAC3 (IC= 8 M). Has no inhibitory activity towards HDAC8 (IC100 M).

More Information
Alternate Name/Synonyms
MS-275, SNDX-275
SKU
M-2358
CAS #
209783-80-2
Chemical Name
[4-(2-AMINO-PHENYLCARBAMOYL)-BENZYL]-CARBAMIC ACID PYRIDIN-3-YLMETHYL ESTER
Chemical Formula
C21H20N4O3
Molecular Weight
376.41
Appearance
Crystalline Solid
Purity
99% by HPLC
Solubility
DMSO (38 mg/ml)
Melting Point
158-160 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
HDAC inhibitor use in cancer
MDL NUMBER
MFCD08272435
CHEMACX
X1441359-3
INCHI
InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)
SMILES
c1ccc(c(c1)N)NC(=O)c2ccc(cc2)CNC(=O)OCc3cccnc3
UN #'S
UN 2811
PACKING GROUP
III
Handling
Protect from light and moisture
GHS PICTOGRAMS
Handling Protect from light and moisture
UN #'S UN 2811
Packing Group III
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