mTOR Inhibitor, Ku-0063794

SKU
M-2359
  • CAS:938440-64-3
  • Formula:C25H31N5O4
  • MW:465.54
  • Appearance:Pale yellow Solid
  • Purity:98% by HPLC

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Product Name Qty
mTOR Inhibitor, Ku-0063794
5 mg
$370.19
mTOR Inhibitor, Ku-0063794
1 mg
$96.82
A potent mTOR (mammalian target of rapamycin) inhibitor (IC= ~10 nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested.
More Information
Alternate Name/Synonyms
rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
SKU
M-2359
CAS #
938440-64-3
Chemical Name
rel-5-[2-[(2R,6S)-2,6-Dimethyl-4-morpholinyl]-4-(4-morpholinyl)pyrido[2,3-d]pyrimidin-7-yl]-2-methoxybenzenemethanol
Chemical Formula
C25H31N5O4
Molecular Weight
465.54
Appearance
Pale yellow Solid
Purity
98% by HPLC
Solubility
DMSO
Storage Temp
-20°C
THERAPEUTIC AREA
Oncological Disorders
USE
A FRAP (mTOR) inhibitor for both mTORC1 and Mtorc2 in cancer
MDL NUMBER
MFCD22666594
CHEMACX
X1759489-7
INCHI
InChI=1S/C25H31N5O4/c1-16-13-30(14-17(2)34-16)25-27-23-20(24(28-25)29-8-10-33-11-9-29)5-6-21(26-23)18-4-7-22(32-3)19(12-18)15-31/h4-7,12,16-17,31H,8-11,13-15H2,1-3H3/t16-,17+
SMILES
C[C@@H]1CN(C[C@@H](O1)C)c2nc3c(ccc(n3)c4ccc(c(c4)CO)OC)c(n2)N5CCOCC5
Peptide sequence
Not Applicable
RTECS
Not Applicable
UN #'S
UN 2811
PACKING GROUP
III
HAZARD CLASS
Not Applicable
Handling
Protect from air and light
GHS PICTOGRAMS
Handling Protect from air and light
UN #'S UN 2811
Packing Group III
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