Myeloperoxidase Inhibitor
SKU
M-2360
- CAS:5351-17-7
- Formula:C7HN3O
- MW:151.17
- Appearance:White to off-white Solid
- Purity:95% by HPLC
SDS
CofA
A potent, irreversible, and specific inhibitor of the peroxidation activity of myeloperoxidase (MPO; IC= 300 nM). Does not affect catalase or glutathione peroxidase activities. Also displays no effect on the production of superoxide by neutrophils. Shown to inhibit H,-induced apoptosis in HL-60, human leukemia cells.
More Information
Alternate Name/Synonyms
4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
SKU
M-2360
CAS #
5351-17-7
Chemical Name
4-Aminobenzoic hydrazide; MPO Inhibitor; 4-ABH
Chemical Formula
C7HN3O
Molecular Weight
151.17
Appearance
White to off-white Solid
Purity
95% by HPLC
Solubility
DMSO
Melting Point
225-227 °C
Storage Temp
-20°C
THERAPEUTIC AREA
Vascular Disorders
USE
An irreversible and specific inhibitor of the peroxidation activity of MPO
MDL NUMBER
MFCD00007606
CHEMACX
X1021455-6
INCHI
InChI=1S/C7H9N3O/c8-6-3-1-5(2-4-6)7(11)10-9/h1-4H,8-9H2,(H,10,11)
SMILES
c1cc(ccc1C(=O)NN)N
Peptide sequence
Not Applicable
RTECS
DG2580000
UN #'S
Not Applicable
PACKING GROUP
Not Applicable
HAZARD CLASS
Not Applicable
Handling
Protect from light and mositure
| GHS PICTOGRAMS |
|
|---|---|
| Handling | Protect from light and mositure |
| UN #'S | Not Applicable |
| Packing Group | Not Applicable |