Nalidixic Acid Sodium is the first quinolone-based antibacterial, inhibiting bacterial DNA polymerase and avian myeloblastoma virus reverse transcriptase. It inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae by suppressing essential bacterial enzymes such as topoisomerases IV and DNA gyrase. It has been reported that, in some specific gram-negative bacteria, Nalidixic Acid shows dose-response patterns of a bactericidal.
In addition, it is used for the treatment of urinary tract infections and is used to study anticancer activity.
• Antibacterial agent
• Used in antitumor studies
Not for human therapeutic use or for medicinal purposes. For research applications only.
|Handling||Use only in area provided with appropriate exhaust ventilation. Keep away from heat and source of ignition. Empty containers pose a fire risk, evaporate residue under fume hood. Ground all equipment containing material. Do not breathe dust.|