Naphthomycin B
SKU
N-2408
- CAS:86825-88-9
- Formula:C39H44ClNO9
- MW:706.2
- Appearance:Yellow solid
- Purity:≥98% (HPLC)
SDS
CofA
Naphthomycin B is an 29-membered naphthalenic ansamacrolactam antibiotic with antimicrobial and antineoplastic activities.
This product is isolated from Streptomyces sp. Gö 40/14.
Ansamycin antibiotics including rifamycin, naphthomycin, ansatrienin(mycotrienin) are structurally related, containing a macrocycle of polyketide origin with an amide linkage to either a naphthalenic or benzenic aromatic moiety.
Product References
Isolation and structural elucidation of naphthomycins B and C, Walter Keller-Schierlein, et al, The Journal of Antibiotics, Vol. 36 (1983)
Cloning and functional analysis fo the naphthomycin biosynthetic gene cluster in Streptomyces sp., Yingying Wu, et al, Mol. BioSyst, 7, 2459-2469 (2011)
Biosynthesis of ansatrienin(mycotrienin) and naphthomycin, Shuo Chen, et al, European Journal of Biochemistry, vol. 261:98-107 (1999)
More Information
SKU
N-2408
CAS #
86825-88-9
Chemical Name
2-Demethylnaphthomycin A
Chemical Formula
C39H44ClNO9
Molecular Weight
706.2
Appearance
Yellow solid
Purity
≥98% (HPLC)
Solubility
Soluble in DMSO, methanol or acetone
Storage Temp
-20°C
| GHS PICTOGRAMS |
|
|---|